• merely A number of studies have shown that zoledronic acid

  2019-05-06

  

  A number of studies have shown that zoledronic merely has the ability to potentiate effects of anti-tumor agents such as doxorubicin [21] or everolimus [22]. In a recent paper the combination of chemotherapy with a single infusion of 4mg zoledronic acid in patients with breast cancer was shown to re

• p53 inhibitor A type saddle back type or

  2019-05-06

  

  A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b

• br Over the past decade global concern about

  2019-05-06

  

  Over the past decade, global concern about the disproportionate burden of disease and mortality in low-income countries, especially in sub-Saharan Africa, has led to a substantial influx of funding for research by many donor and research agencies. This investment has energised in-country research;

• More than structural haemoglobin variants

  2019-05-06

  

  More than 900 structural haemoglobin variants have been described. Of these more than 100 show high oxygen affinity [2]. Erythrocytosis caused by Hb Ypsilanti was first described in 1967 [3], and the mutation results in substitution of amino bupropion hydrochloride (β99 Asp→Tyr) involved in the stab

• Education is part of the

  2019-05-06

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres

• A structured inherited arrhythmia or heart disease clinic

  2019-05-06

  

  A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli

• br Components of a remote monitoring system The components

  2019-05-06

  

  Components of a remote monitoring system The components constituting a remote monitoring system [27] consist of: Which parameters to monitor? The above is an overview of the currently available sensors for CRT. As can be seen from previous studies, not all of these sensors will lead to favora

• br Conflict of interest br Introduction

  2019-05-06

  

  Conflict of interest Introduction Antiarrhythmic device lead implantation using the cephalic vein (CV) cutdown technique is considered to be superior to the conventional subclavian vein puncture method with regards to the incidence of perioperative complications such as pneumothorax [1,2] and

• We have recently completed a prospective randomized feasibil

  2019-05-06

  

  We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co

• br Reimbursement system The current reimbursement regulation

  2019-05-06

  

  Reimbursement system The current reimbursement regulations are in need of an update [26,27]. In 2008, the Centers for Medicare and Medicaid Services in the USA approved a revised set of codes developed in collaboration with HRS, the American College of Cardiology, and the American Medical Associa

• Introduction Several types of cancers including those origin

  2019-05-06

  

  Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s

• br Conclusion Our findings may help physicians in selecting

  2019-05-06

  

  Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic fluvastatin is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it

• An ERP in the ECG has been shown to

  2019-05-06

  

  An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A

• La eleg a de tus ojos Uno

  2019-05-06

  

  “La elegía de tus ojos” (1914) Uno de los poemas más tempranos de Pellicer, “La elegía de tus ojos”, ya demuestra un sentido nuevo de historicidad. Escrito en 1914, en el apogeo del posmodernismo y durante la Revolución mexicana, cuando el poeta tenía apenas unos quince años, este poema se adhiere

• br The Ministerial Conference on in

  2019-05-06

  

  The Ministerial Conference on in Asia and the Pacific is taking place on Nov 24–28, 2014, in Bangkok, Thailand. In recognition of this and parallel plans from the UN Economic Commission for Africa for a Ministerial Conference on CRVS for African countries, to be held in Côte d\'Ivoire in February

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