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Introduction Several types of cancers including those origin
2019-05-06
Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s
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br Conclusion Our findings may help physicians in selecting
2019-05-06
Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic fluvastatin is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it
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An ERP in the ECG has been shown to
2019-05-06
An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A
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La eleg a de tus ojos Uno
2019-05-06
“La elegía de tus ojos” (1914) Uno de los poemas más tempranos de Pellicer, “La elegía de tus ojos”, ya demuestra un sentido nuevo de historicidad. Escrito en 1914, en el apogeo del posmodernismo y durante la Revolución mexicana, cuando el poeta tenía apenas unos quince años, este poema se adhiere
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br The Ministerial Conference on in
2019-05-06
The Ministerial Conference on in Asia and the Pacific is taking place on Nov 24–28, 2014, in Bangkok, Thailand. In recognition of this and parallel plans from the UN Economic Commission for Africa for a Ministerial Conference on CRVS for African countries, to be held in Côte d\'Ivoire in February
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cysteine protease inhibitor Several mechanisms have been pro
2019-05-06
Several mechanisms have been proposed. Due to a greater birth interval, children who are breastfed will enjoy a greater period of exclusive parental attention as either the only child or youngest child. This exclusivity might have an effect on intelligence. It has been consistently observed that the
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br LEGADO FUJIMORISTA No seu
2019-05-05
LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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Uric acid level was high at presentation but not
2019-05-05
Uric phalloidin level was high at presentation but not at a level where nephropathy is usually expected. Yet, uric acid increased with creatinine until administration of rasburicase. Whether this increase was enough to cause or contribute to the ARF is uncertain. Comparably, Larsen and Loghman-Adha
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The estimated annual burden of injury in rural
2019-05-05
The estimated annual burden of injury in rural Bangladesh revealed by this study was striking; 44 050 deaths and 21 million people suffering major injury events annually that were severe enough for them either to be unable to go to work or school for a day, or severe enough for them to seek treatmen
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Missed cases have been reported who had an
2019-05-05
Missed cases have been reported who had an initially elevated C5DC concentration that normalized on a repeated sample. Such a result may be caused by secondary carnitine depletion. To avoid carnitine depletion, we propose that the carnitine loading test be used to assist diagnosis of GA-1. Although,
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HF is associated with the down regulation of multiple potass
2019-05-05
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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br Bisphosphonate use and breast cancer risk BPs are commonl
2019-05-05
Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites
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In this issue of the
2019-05-04
In this issue of the , Shoja et al characterize the antimicrobial susceptibility pattern, resistance mechanisms, and typing of carbapenem-resistant (CRAB) isolates obtained from burn patients from a single center in Iran. They found that the rate of CRAB was high (92.5%) among burn patients. The mo
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br Case report A year old
2019-05-04
Case report A 41-year-old woman who had been fitted with a pacemaker for bradycardia 18 years prior presented for lead extraction on account of device infection. She had a left pectoral dual chamber pacemaker, with two tined leads: an atrial lead of 5524 M (Medtronic, Dublin, Ireland) and a ventr
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Estas ideas permanecieron vigentes durante mucho
2019-05-04
Estas ideas permanecieron vigentes durante mucho tiempo antes de la revolución científica desatada por el racionalismo. Un ejemplo es cómo las nociones neumáticas —derivadas de la idea de que el mundo fue creado por un soplo divino— todavía son palpables en el Primero sueño de sor Juana cuando inici
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