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Recent studies have shown arsenic could cause autophagic
2021-06-29
Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma Pirarubicin receptor [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its related
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br Acknowledgment S A was supported by V
2021-06-28
Acknowledgment S.A was supported by V Plan Propio US-AccesoUSE-14793-G. Introduction Neutrophils are innate immune 25-hydroxyvitamin d3 of primary importance for protecting against infections by microorganisms [1,2] through various antimicrobial abilities, including microorganism phagocytosi
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Accumulating evidence suggests that certain abnormal emotion
2021-06-28
Accumulating evidence suggests that certain abnormal emotional traits, such as impulsive aggression and cluster B personality, are associated with suicidal behaviors (Currier and Mann, 2008, Mann et al., 2009, Rujescu et al., 2007, Turecki, 2005). Impulsive aggression appeared to be associated with
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Though the physiological roles of microglia
2021-06-28
Though the physiological roles of microglia-derived elastases in the CNS are not well understood, their involvement in the metabolism of cholecystokinin [41] and in the processing of plasminogen to produce a low molecular weight plasminogen that enhances neurite outgrowth has been reported [38]. Exp
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On the other hand the interaction of the Kaempferia parviflo
2021-06-28
On the other hand, the interaction of the Kaempferia parviflora extract with CYP3A was uncompetitive with a low Vmax value. In the in vivo study, the Kaempferia parviflora extract did not interfere with CYP3A activity throughout the entire duration of treatment. This is fortunate as CYP3A isoforms a
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To assess whether the described cooperation
2021-06-28
To assess whether the described cooperation between the EGFR and FGFR receptors was relevant at the clinical level, we determined the effect on progression-free survival of FGFR1 expression in patients with adenocarcinoma who were receiving erlotinib or gefitinib. As we had observed EGFR-FGFR1 coope
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The fact that the mean tumor size of
2021-06-28
The fact that the mean tumor size of the E1202-654 + α-GalCer group was much smaller than that of the α-GalCer inoculated group in both protocols indicates that immunization with E1202-654 plus α-GalCer, which induces a strong CD8+ T cell E1 antigen-specific immune response, is involved in the elimi
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DSBs can be repaired by two major pathways
2021-06-28
DSBs can be repaired by two major pathways: canonical non-homologous end-joining (c-NHEJ) and homologous recombination (HR) (Chapman et al., 2012). c-NHEJ comprises two sub-pathways, a resection-independent process and a resection-dependent process, and can rejoin break ends with little or no sequen
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There are a few visible DNA staining
2021-06-28
There are a few visible DNA staining methods, which use dyes such as methylene blue, brilliant cresyl blue [7], crystal violet [8], Nile blue [9], [10] and ethyl violet [11]. However, although safe, these methods require long staining times, lack sensitivity and are not specific for nucleic acids.
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In the growth of cereal seeds there
2021-06-28
In the growth of cereal seeds there are two phases, development and germination, separated by dormancy. The developmental phase contains the three following stages: 1. early development including double fertilization which results in the formation of the diploid embryo (by fusion of the egg cell wit
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Large yellow croaker Larimichthys crocea are widely cultured
2021-06-28
Large yellow croaker (Larimichthys crocea) are widely cultured in China but have inferior meat texture compared with wild fish. This result results from excess lipid deposition in the muscle, which reduces mechanical strength (Thakur et al., 2003). The liver is the central of lipid metabolism and st
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According to these results the power
2021-06-28
According to these results, the power GaN seems more robust than existing technologies (VDMOS, Superjunction, IGBT,) [5,10] and [11]. Comparing with the SiC technology, the previous works show a low SEE tolerance [[12], [13], [14]] and [15]. The SOA of power GaN devices can be equivalent to the IGBT
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br Funding sources br Introduction Psychiatric comorbidities
2021-06-25
Funding sources Introduction Psychiatric comorbidities affect up to 70% of people with pharmacoresistant epilepsy and significantly impact quality of life [1]. Psychiatric comorbidities in epilepsy have been thought to be due to psychosocial stress. However, recent evidence suggests a more com
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TDZD-8 br Conflicts of interest br
2021-06-25
Conflicts of interest Acknowledgments This research was supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science, ICT and Future Planning (NRF-2015R1A2A2A01004593). Introduction Resistance to Inhibitors of Cholinest
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Early tubular differentiation in WT lacks
2021-06-25
Early tubular differentiation in WT lacks lumen formation and, therefore, sometimes can be confused with rosettes of ES/PNET or neuroblastoma. However, tubular structure usually has hop over to these guys neatly aligned to form a single layer around the future lumen, whereas neuroblastic rosettes a
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