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Progesterone s metabolite THP may also be mediating
2020-09-07

Progesterone\'s metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, tcY-NH2 and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Evans rat admini
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br ANTITHROMBOTIC TREATMENTS br VOLUME
2020-09-07

ANTITHROMBOTIC TREATMENTS VOLUME-OUTCOME RELATIONSHIP FOR REVASCULARIZATION PROCEDURES The guidelines also maintain the recommendations for training in PCI, both for ACS (≥ 75 procedures per operator in centers with at least 400 PCI procedures per year and a 24-hour on-call service) and for st
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Similarly EGCG restored the mitochondrial energy
2020-09-07

Similarly, EGCG restored the mitochondrial energy shortfall in fibroblasts and lymphoblasts of the patients affected by Down syndrome, even so the mechanism of the effect was not clearly known (Valenti et al., 2013). EGCG also stimulated the mitochondrial biogenesis by activation of nuclear respirat
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Plasminogen is composed of five N terminal kringle domains a
2020-09-07

Plasminogen is composed of five N-terminal kringle domains and a C-terminal serine protease domain. The kringle domains have an affinity to lysine and binding of plasminogen with its receptors is dependent on its lysine interacting kringle domains [10], [28]. In the current report, we show that enol
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The contribution of local ETA
2020-09-07

The contribution of local ETA and ETB receptors towards heat hyperalgesia induced by inoculation of XC tumor MCC950 sodium synthesis in the paw of mice has been demonstrated by Baamonde and colleagues (Baamonde et al., 2004). Furthermore, using neuropathic and inflammatory nociception models, severa
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For statistical analysis the Statistical Package for Social
2020-09-07

For statistical analysis, the Statistical Package for Social Sciences (SPSS) was used (version 21.0; SPSSInc., Chicago, IL). Chi-square (x2) exact test was used for the comparison of categorical data, whereas Wilcoxon and Mann–Whitney U tests were used for the analysis of nonparametric variables bas
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Introduction Numerous professional governmental and
2020-09-05

Introduction Numerous professional, governmental, and media sources report a strong demand for and even a scarcity of new entrants to the fields of professional accounting and auditing. Furthermore, reports emphasize expectations of continuing high demand in the future (AICPA, 2015, Manpower Group,
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The ERR gene lacks the typical TATA and
2020-09-05

The ERRα gene lacks the typical TATA and CAAT boxes, but has multiple consensus Sp1 binding elements in the GC-rich promoter (Shi et al., 1997). Previously, our laboratory has shown that ERRα expression is upregulated in the mouse uterus by estrogen (Shigeta et al., 1997) and recently we identified
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br STAR Methods br Acknowledgments We thank
2020-09-05

STAR★Methods Acknowledgments We thank members of R.L. lab and F. Schweisguth for critical reading of the manuscript. We are also grateful to F. Janody, M. Miura, C. Bökel, H.D. Ryoo, G. Jiménez, the Bloomington Drosophila Stock Center, the Drosophila Genetic Resource Center, the Vienna Drosoph
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CYP A and CYP D are among the main drug
2020-09-05

CYP3A4/5 and CYP2D6 are among the main drug-metabolizing enzymes in humans that are responsible for the metabolism of more than 50% of marketed drugs [19], [21]. Drugs metabolized by CYPs are prone to drug–drug interactions, thereby modifying their response [18], [32]. Metabolic inhibition is also i
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Materials and methods Between January and December
2020-09-05

Materials and methods Between January 2006 and December 2008, 34 patients with GBM were treated with postoperative three-dimensional (3D) radiotherapy at Tartu University Hospital or North Estonian Medical Centre. Characteristics of patients are listed in Table 1. Results Discussion Radiothe
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Currently approved anti obesity drugs for long term use
2020-09-05

Currently approved anti-obesity drugs for long term use such as orlistat, lorcaserin and liraglutide are efficient in reduction of weight gain but are limited in usage due to their adverse effect profile and higher cost (Krentz et al., 2016; Mopuri and Islam, 2017). In cid calculator to this, plant
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Why then is leading strand DNA synthesis
2020-09-04

Why then is leading-strand DNA synthesis reduced relative to lagging-strand synthesis in rad53-1 mutant NS3694 under replication stress? To gain insight into this question, we first determined whether the firing of late origins in rad53-1 mutant cells contributes to compromised leading-strand synth
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For radiochemotherapy it is well
2020-09-04

For radiochemotherapy, it is well known that mitotic cell death and apoptosis present the major cell death modes. More recently, autophagy-dependent cell death has been described to occur upon radiochemotherapy (Daido et al., 2005, Song et al., 2017). This form of regulated cell death depends on com
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Finally the recent work to define the
2020-09-04

Finally, the recent work to define the microcircuitry of the central amygdala and the role of specific cell populations in fear conditioning can stand as a useful model for advances in preclinical alcohol research. To date, the role of the amygdala in alcohol-related behaviors, and reward-related be
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