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The PAX gene encodes a transcriptional factor
2019-06-06
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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Analyses such as those used by Burke and
2019-06-06
Analyses such as those used by Burke and colleagues rely on periodic cross-sectional surveys that are not linked to available or civic registration and vital statistics databases. These surveys are also limited by the inevitable time lag between analyses and feedback to health systems and policy mak
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br Methods br Results A total
2019-06-06
Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer
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Curative treatments which include surgical
2019-06-06
Curative treatments, which include surgical resection, percutaneous ablation and liver transplantation, were considered as the optimal treatment for patients with very early/early stage HCC by BCLC criteria. Furthermore, advances in liver surgery make the resection of large and/or multifocal HCC pos
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The majority of breast malignancies are hormone responsive a
2019-06-06
The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno
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PROFACE aimed to investigate the efficacy of
2019-06-06
PROFACE aimed to investigate the efficacy of atorvastatin in preventing POAF and SIRS. Atorvastatin, 40mg/day, was administered 7 days before and after elective bupropion hydrochloride valve surgery in a randomized patient population with no preoperative beta-blocker treatment or previous episodes o
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Vollmer and colleagues distinctive multilevel modelling has
2019-06-06
Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau
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Contrario a lo que concluye
2019-06-06
Contrario fluvastatin sodium lo que concluye Guajardo, en torno a que la privatización dejó de lado el tema central de la reforma del Estado y de las nuevas capacidades públicas, de ahí que los efectos de décadas de reformas económicas sean todavía confusos e inconsistentes, el fenómeno globalizador
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protease inhibitors hiv To the best of our knowledge only on
2019-06-06
To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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The miR signature of exosomes isolated from bulk prostate ca
2019-06-05
The miR signature of exosomes isolated from bulk prostate cancer nfps (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key regulators of o
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Introduction Verapamil sensitive idiopathic left ventricular
2019-06-05
Introduction Verapamil-sensitive idiopathic left ventricular tachycardia (ILVT) has been shown to be a clinical entity of left-sided idiopathic ventricular tachycardia (VT) [1,2]. In electrophysiological studies, two specific local potentials, the diastolic Purkinje (Pd) potential and presystolic P
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Antenatal corticosteroids induce fetal lung maturation throu
2019-06-05
Antenatal corticosteroids induce fetal lung maturation through the same biological mechanism in low-income settings as in high-income settings and reduce the need for neonatal mechanical ventilation. Although antenatal corticosteroids might not be a so-called magic bullet as a standalone vertical in
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En el libro de Morales Carazo este transparente
2019-06-05
En el libro de Morales Carazo este transparente desciframiento del nacionalismo oculto de los “contras”, se produce con MLN9708 en un acto de enmascaramiento literario, que refiere a Pablo Antonio Cuadra. El autor hace una lectura del sujeto campesino y sus valores a partir de su convivencia con los
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Consider international terrorism a growing
2019-06-05
Consider international terrorism; a growing threat to which conventional “hard power” responses have had limited success in addressing. What could, or should, global health do about it? Dissociate (as advocated by the Deans of the US medical schools), isolate, establish boundaries, and “stove-pipe”?
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FD appears radiographically as radiolucent areas which later
2019-06-05
FD appears radiographically as radiolucent areas which later develop into a partially opaque ground glass appearance [51]. Other features that may be present are endosteal scalloping, bony expansion, and a thick reactive bone ‘rind’ [54]. MR imaging may be a more effective tool at identifying the si
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