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With regard to the correlation between rearrangements and th
2024-08-29
With regard to the correlation between -rearrangements and thromboembolic events, Zer et al. reported a VTE rate of 36% in a cohort of 98 patients with ALK-positive NSCLC. Of note, VTE was also associated with shorter overall survival (HR: 5.71, =0.01) . Only few others have investigated NSCLC drive
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The anorexic effect observed when AR is infused into the
2024-08-29
The anorexic effect observed when AR231630 is infused into the VTA could be the result of the DA release inhibition, as previously described [11]. However, there is also a hedonic aspect in feeding that possibly involves dopaminergic mechanisms of reward. Helm et al. showed a functional link between
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Renal cell carcinoma RCC accounts for more than
2024-08-28
Renal cell carcinoma (RCC) accounts for more than 12,000 cancer deaths in the United States (Jemal et al., 2003). The current treatment includes surgical resection followed by interleukin-2 or Interferon-α treatment. Some patients experience distant metastatic lesions of RCC. In the last 5 years, re
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br In our experience br
2024-08-28
In our experience History of ER and ACh tests As shown in Table 1, Stein et al. first reported the usefulness of intravenous injection of ER in diagnosing coronary insufficiency in 1949 [16]. In 1972, the first ER spasm provocation test was employed at the Cleveland Clinic during cardiac cathe
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vasopressin receptor antagonist The role of DHT in
2024-08-28
The role of DHT in early teleost embryogenesis is not entirely clear or established, however additional studies that treat fish embryos to DHT or to specific srd5a inhibitors at critical stages of development (i.e. prior to sex differentiation) will shed light on the early functions of this androgen
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Matsuzaki et al attempted fertility therapy in a year
2024-08-28
Matsuzaki et al. attempted fertility therapy in a 26-year-old female with secondary amenorrhea and 17OHD who was a MMP-2/MMP-9 Inhibitor I mg heterozygote for delF53/54 and the missense mutation H373L, which has when hypertension and hypokalemia are present. Milder cases of 17OHD might be assumed t
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Chloramphenicol Mistletoe is universal name for various spec
2024-08-28
Mistletoe is universal name for various species of parasitic plant which grows attached to and within the branches of host trees such as apple, elm, oak and pine. Mistletoe extract prepared from Viscum album, a species of mistletoe in the family Santalaceae, is generally known as European mistletoe
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At present the role of autophagy in neurons remains
2024-08-28
At present, the role of autophagy in neurons remains controversial. Autophagy has homeostatic and waste-recycling functions and plays a protective role in neurodegeneration diseases. Moreover, it has been thought as a programmed cell death participating in the occurrence and development of various d
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br Materials and methods br
2024-08-28
Materials and methods Results Discussion Numerous studies showed that Na+-K+-ATPase activity and membrane Aclacinomycin A were decreased in cardiac tissue subjected to IR (Belliard et al., 2013; Lee et al., 2013). In return, treatment that alleviated the progress of IR-related myocardial i
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Demonstration of in vivo efficacy of potential chemopreventi
2024-08-28
Demonstration of in vivo efficacy of potential chemopreventive agents in animal models is necessary for their clinical development. Our present study provides experimental evidence that CuB 0.1μmol by oral administration (for 2weeks before the cancer cell injection, 5days per week) significantly inh
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Based on its kinetic parameters
2024-08-28
Based on its kinetic parameters and quaternary structure, R. pycnus arginase is a typical ureotelic L-arginase [2]. The Km value of the enzyme was lower than other arginases from other organisms (Table 2), including S. cerevisiae (15.7mM), B. anthracis (10mM), B. caldovelox (3.4mM), human liver (2.3
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Finally impaired endothelial integrity culminates
2024-08-28
Finally, impaired endothelial integrity culminates in an increased plasma protein concentration in the interstitial space, and thus accumulation of fluid in the ECM, favoring the swelling of the face and limbs [2] mainly. Concurrently with this systemic change, there is intense activation of coagula
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Although sex hormones activational effects are known to
2024-08-28
Although sex hormones (activational effects) are known to directly interact with RAS (Baiardi et al., 2005, Miller et al., 1999, Silbiger and Neugarten, 1995), the potential contribution of organizational hormonal and SCC effects on physiological sex-based difference in the regulation of the RAS rem
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Aggregated A species have been studied by an array of
2024-08-28
Aggregated Aβ species have been studied by an array of biophysical techniques, including atomic force microscopy (AFM) [55], transmission electron microscopy (TEM) [56], [57], X-ray diffraction [58], Fourier transform infrared (FTIR) [59], [60], circular dichroism (CD) [61], and nuclear magnetic res
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br Neurological development and BCAAs Glutamate is an
2024-08-27
Neurological development and BCAAs Glutamate is an important excitatory neurotransmitter in the brain, and BCAAs (especially leucine) function to synthesize glutamate in astrocytes around neurons, since leucine enters the brain from the blood more rapidly than other U 18666A and provides ∼25% of
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